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Flow Fluorescence Technology – In Vitro Diagnostic Products Section

2025/10/25 15:37:00

Flow fluorescence technology is a clinically applied high-throughput luminescent detection technology based on encoded microspheres and flow technology. It is also known as liquid chip, suspension array, Luminex? xMAP technology, and more. As a new-generation high-throughput molecular diagnostic technology platform following biochip technology and chemiluminescence technology, it has become a major focus in the field of clinical diagnosis and life science research. This technology integrates the advantages of colored microspheres, applied fluidics, laser technology, and high-speed digital signal processing technology. Currently, it has been widely used in research fields such as immunoassays, nucleic acid detection, enzymatic analysis, and receptor-ligand recognition analysis. It possesses multiple advantages: it enables simultaneous detection of multiple indicators, offers high throughput and fast speed, requires small sample volumes, can detect both nucleic acids and proteins, and is applicable to both clinical testing and scientific research—making it the "dream technology" for every laboratory professional. Over nearly 20 years of development, flow fluorescence technology has integrated technologies including fluorescently encoded microspheres, laser detection, and signal processing. For the key qualitative and quantitative detection of nucleic acids or proteins, the signal can be amplified through labeled biotin and streptavidin-phycoerythrin (SA-PE); alternatively, direct labeling with phycoerythrin (PE) is also feasible. This truly realizes a high-tech solution characterized by automation, high-throughput testing, low cost, and high sensitivity.

At present, it has been widely adopted by major domestic clinical testing enterprises in China to establish independent reagent development platforms. It is applied in numerous fields, including HLA panels, autoimmune disease detection, allergen detection, gene mutation detection, tumor marker detection, and HPV genotyping.

Technical Platform Application Classification Product
Concord Locke
(BejingUnionluck) 
Luminex XMAP
Cardiovascular and cerebrovascular diseases Lipoprotein phospholipase A2 (Lp-PLA2) assay kit Myeloperoxidase assay kit
Troponin T (cTnT) assay kit
Myeloperoxide, lipoprotein phospholipase A2, and troponin T combined assay kit
Multiple cardiovascular markers; (H-FABP, NT proBNP, MYO, CK-MB, cTnT) assay kit
Creatine kinase isoenzyme (CK-MB) assay kit
Heart type fatty acid binding protein (H-FABP) assay kit
Myoglobin (MYO) assay kit
N-terminal pro brain natriuretic peptide (NT proBNP) assay kit
Guosheng Medicine
(ABIOM) 
Microfluidic Control Testing Center
Precision medication for tumors Enhanced liquid biopsy for all cancer types
Pan cancer panoramic version genetic testing
Panoramic version of gene testing for lung cancer
Single gene testing
Homologous recombination repair:; HRD pancreatic cancer/prostate cancer/ovarian cancer/breast cancer
Single fusion gene:; Tumor gene fusion detection/EML4-ALKK/ALK, RET, ROSI gene fusion
Cardiovascular and cerebrovascular diseases Cholesterol balance test
Molecular testing for precise medication for lowering blood lipids
Genetic and pharmacogenomic testing for cardiovascular and cerebrovascular diseases
Molecular testing for precise anticoagulant drugs
Molecular detection of precise medication for lowering blood pressure
infectious diseases Respiratory infection - COV19  Detection
16S RNA detection of gut microbiota
Metagenomic sequencing detection
Neurological disorders Topiramate drug genetic testing
Genetic testing for anti dementia drugs
Okazepine drug gene testing
Individualized genes for Alzheimer's disease Pharmacogenomic testing
Family epilepsy gene testing
Genetic testing of levetiracetam drug
Sodium valproate drug genetic testing
Epilepsy generation validation
Rheumatic and immune diseases Detection of functional gene expression in immune cells
Gout pathogenesis gene+personalized medication gene testing
HLA-B27 typing
Severe immune gene deficiency; (SCID)  Quantitative testing
Detection of susceptibility genes and drug genes of diabetes
High throughput gene testing for severe immune gene defects
Comprehensive detection of combined immune gene defects; (CPIP)
Popular health products Analysis and measures of sun protection ability
Hair quality classification and care
Classification and prevention of susceptibility to acne
Analysis and suggestions on six aspects of endocrine balance
Analysis and maintenance of anti-aging ability
Analysis and Measures of Radiation Protection Capability
Obesity risk and weight loss recommendations
Analysis and Prevention of Allergic Constitution Complete set of beauty genetic testing
Anti wrinkle ability analysis and maintenance
Risk and Prevention of Freckles and Melanin
Evan Biology
(Shanghai  IvenBiotech)
FLEXMAP  3D® System/
Luminex® 200™ System/

  MAGPIX® System
Tumor Diagnosis Multi tumor biomarker (5 types) detection kit
Combination of eight tumor markers for joint testing
Free/Total Prostate Specific Antigen Test Kit
Carbohydrate antigen 15-3/human epididymal protein 4 detection kit
Di Mai Biology
(DymindBiotechnology)
— — Procalcitonin/interleukin-6 assay kit Aldosterone/Renin Assay Kit
Troponin I/creatine kinase isoenzyme/myoglobin assay kit
Allergen specific IgE antibody detection kit
N-terminal atrial natriuretic peptide (NT proBNP) assay kit
New Vertical Science
New Branch
NovaHT
Cytokines Twelve cytokine detection kits
Only Public
Wellgrow
EasyPlex2200
Tumor markers CEA/CA125/CA19-9 detection kit
CA125/HE4 detection kit
CEA/SCC/CYFRA21-1/NSE/proGRP detection kit
Alpha fetoprotein (AFP) detection kit
CEA/SCC/CYFRA21-1 detection kit
CEA/CA15-3 detection kit
Note: Weigong related products are directly marked with PE
Saiki Biotech
(Cellgene biotech)
  Human Th1/Th2/Th17 Subset Detection Kit
Immunoglobulin G Subclass Detection Kit
Chemokine Combined Detection Kit
Programmed Death Protein-1 Detection Kit
Soluble Inflammatory Factor Four Test Kit
Tumor comprehensive immune assessment six factor combined detection kit
Biobank
(Biopredia Biological)
Luminex 200/
PD6800Pro
Reproductive endocrine Sex Hormone Six item Joint Inspection Kit
Thyroid Thyroid function five item joint test kit
Perspective
(Tellgen Corporation)
Luminex 200
TESMI-F4000
Tumor markers Twelve item detection combination for tumor markers
Seven detection reagents for tumor markers
Multi tumor joint inspection - male 9 female 8
AFP/CEA  Two quantitative testing agents
Five lung tumor markers
Joint detection of three tumor markers for lung cancer
PGI/PGII  Quantitative detection kit
G17 assay kit
F-PSA/f-PSA quantitative detection
Liver fibrosis four items
ProGRP  Testing reagents
HE4 detection
AFP Quantitative Detection Kit
CEA quantitative detection reagent
CA724 Quantitative Detection Kit
CYFRA21-1 quantitative detection reagent
SCCA quantitative detection kit
CA125 Quantitative Detection Kit
CA153 Quantitative Detection Kit
CA199 Quantitative Detection Kit
CA50 Quantitative Detection Kit
NSE Quantitative Detection Kit
CA242 Quantitative Detection Kit
HPV typing of cervical cancer HPV27  Nucleic acid typing test kit
Fecal occult blood Human Fecal Hemoglobin (HB)/Transferrin (TF) Test Kit
Reproductive Health Toxoplasma gondii, rubella virus, cytomegalovirus, herpes simplex type 1, herpes simplex type 2 IgG/IgM antibody detection kit
Cardiovascular and Cancer Liver fibrosis biomarker four item assay kit
Autoimmune infections Sixteen autoantibody spectrum detection reagents
CCP antibody testing
APS antibody assay
Three types of vasculitis
Self encouragement liver antibody spectrum determination
Anti phospholipase A2 receptor antibody
Huijin Chuangxing
(Bright-Innovation BioMed)
Luminex
Genetic diseases Brittle  X  Syndrome gene testing
Genetic testing for spinal muscular atrophy
Genetic testing for non syndromic hereditary hearing loss
Early diagnosis of nasopharyngeal carcinoma
Risk assessment of cervical cancer in patients with high-grade lesions
HPV  Risk assessment of cervical cancer in high-risk infection patients
Postoperative evaluation of colorectal cancer
Early diagnosis of colorectal cancer
Individualized medication Gene testing for drug-induced hearing loss
Individualized gene testing of anticoagulant drugs for cardiovascular and cerebrovascular diseases
Individualized medication genetic testing for angina patients
Individualized medication gene testing for patients with hyperuricemia and gout
Individualized folate gene testing

Crystal Biology is capable of extracting and purifying phycobiliproteins at the reagent grade. These phycobiliproteins feature a fluorescence ratio and purity higher than the industry average. Additionally, the company provides streptavidin-labeled phycoerythrin (SA-PE) products with strong fluorescent signals, high signal-to-noise ratio, and low non-specificity. It stably supplies such products and related services to world-renowned biotechnology companies and clinical diagnostic companies.

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